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CBS INSIGHTS: Recent Developments in Efficient Study Design
CBS INSIGHTS brings together researchers and practitioners to explore innovative ideas, methods, and applications in behavioural science. In this session, “Recent Developments in Efficient Study Design,” Dominique-Laurent Couturier from the University of Cambridge introduces new, smarter ways to run experimental studies.
In contrast to fixed trial designs, which consider pre-defined and unchanging protocols throughout the study, innovative trial designs allow for the dynamic adaptation of trial procedures based on interim analyses. This talk will focus on recent development in Multi-Arm Multi-Stage (MAMS) designs that allow for the dropping of experimental arms before the end of a trial – either for efficacy or futility – based on pre-specified efficacy and futility bounds, thereby allowing for a more optimal allocation of resources and reducing the risk of exposing patients to ineffective treatments.
Join us in the Psychology Department (Room L68) on June 1, 2:00–3:00 pm for an inside look at how to run adequately-powered experiments in new, smarter ways preserving resources.
About the Speaker
Dominique is an Assistant Research Professor at the MRC Biostatistics Unit, University of Cambridge. His work focuses on efficient study designs, multivariate equivalence testing and Bayesian and frequentist adaptive trials.
He also leads the statistics team of the Papworth Trial Unit, supporting clinical studies conducted at Royal Papworth Hospital.